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. 2021 Nov 2;14:211. doi: 10.1186/s13068-021-02059-w

Table 1.

QTLs called by forward selection regression. List of QTLs with an influence on fermentation parameters, the production of extracellular metabolites and volatile secondary metabolites (Additional files 3, 4, 5)

QTL Trait Chromosome Start [bp] End [bp] PVAL range Candidate genes within
SUC2 1-Propanol conc IX 27,399 36,687 6.7–37.8 NIT1
Ethyl acetate conc SUC2
Isoamyl alcohol conc YIL166C
Ethanol conc YIL169C-Gene
Acetic acid conc
Glycerol conc
IMA1 Ethyl acetate conc VII 1,066,563 1,066,735 7.3–42.0 BIO2
Isobutanol conc IMA1
Phenethyl acetate conc
Acetic acid conc
Glycerol conc
Maltose growth
ALD6 Ethyl octanoate conc XVI 432,771 434,477 8.1–112.4 ALD6
Isoamyl alcohol conc
Acetic acid conc
URA5 Ethyl octanoate conc XIII 56,990 56,990 10.5–115.2 URA5
Acetic acid conc
Acetic acid tolerance
Ethanol tolerance
Halotolerance
URK1 Isobutanol XIV 646,585 648,789 8.2 URK1