Table 2.
Associations of family history and the genetic risk score with diabetes in participants from two communities
| Heritable risk factor | Songnan community | Youyi community | ||||
|---|---|---|---|---|---|---|
| No. participants | OR (95% CI) | No. of participants | OR (95% CI) | |||
| Model 1 † | Model 2 ‡ | Model 1 † | Model 2 ‡ | |||
| Genetic risk score | ||||||
| Low | 3,191 | 1 (ref) | 1 (ref) | 2,612 | 1 (ref) | 1 (ref) |
| High | 3,180 | 1.46 (1.30−1.64) | 1.57 (1.39−1.77) | 2,613 | 1.64 (1.40−1.93) | 1.67 (1.42−1.96) |
| Family history | ||||||
| No | 5,461 | 1 (ref) | 1 (ref) | 4,369 | 1 (ref) | 1 (ref) |
| Yes | 910 | 2.65 (2.27−3.09) | 2.78 (2.37−3.26) | 856 | 3.57 (2.95−4.33) | 3.67 (3.01−4.46) |
CI, confidence interval; OR, odds ratio.
†
Model 1 was adjusted for age and sex.
‡
Model 2 was adjusted for age, sex, education attainment (less than high school, high school or further education), waist circumstance, body mass index, hypertension (yes, no) and dyslipidemia (yes, no).