Table 2.

Number and incidence rate of cardiovascular events in older patients with diabetes mellitus

	All	Group 1	Group 2	Group 3	Group 4
HbA1c range (%)	–	<6.3	6.3 to <6.6	6.6 to <7.2	≥7.2
No. patients	3,946	973	785	1,177	1,011
Composite of cardiovascular events
No. patients	142	33	23	30	56
Incidence rate (per 1,000 person‐years)	14.6	13.2	11.7	10.1	24.5
P‐value †	–	–	0.882	0.562	0.001
Stroke
No. patients	54	12	11	14	17
Incidence rate (per 1,000 person‐years)	5.4	4.7	5.5	4.6	7.2
P‐value †	–	–	0.449	0.891	0.104
Cardiac disease
No. patients	85	18	12	16	39
Incidence rate (per 1,000 person‐years)	8.7	7.2	6.0	5.3	16.9
P‐value †	–	–	0.672	0.682	<0.001
Coronary revascularization
No. patients	51	10	8	10	23
Incidence rate (per 1,000 person‐years)	5.1	3.9	4.0	3.3	9.8
P‐value †	–	–	0.971	0.712	0.011
Severe hypoglycemia
No. patients	20	6	1	3	10
Incidence rate (per 1,000 person‐years)	2.0	2.3	0.5	1.0	4.2
P‐value †	–	–	0.078	0.170	0.149
Fracture
No. patients	181	51	29	54	47
Incidence rate (per 1,000 person‐years)	18.7	20.6	14.7	18.3	20.4
P‐value †	–	–	0.471	0.439	0.775

HbA1c, glycated hemoglobin.

^† The generalized Wilcoxon test was used to compare the incidence rate with group 1.