Figure 2: INCA-6 inhibits IL-1β-induced cytokine expression in hRMEC.
hRMEC were treated for 2hr with 1ng/mL IL-1β with or without 5μM INCA-6. Cells were collected and assayed for expression of (A) IL-1β, (B) TNFα, (C) IL-8, (D) IL-6, (E) CCL2, or (F) CCL5. Expression data are reported as fold induction over vehicle with bars representing mean +/− SD (n=3).