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. 2021 Oct 20;15:747681. doi: 10.3389/fnsys.2021.747681

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Copyright © 2021 Sand, Arkadir, Abu Snineh, Marmor, Israel, Bergman, Hassin-Baer, Israeli-Korn, Peremen, Geva and Eitan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in cortical activity per condition. The average of group topoplot 40 ms before and 150 ms after stimulation reveals a different cortical activity in terms of spatial and time specifics, mostly around 50–100 ms, elicited by DBS in three right STN locations [top down: (A) zona incerta (N = 20), (B) DLR (N = 23), (C) VMR (N = 18)]. The X axis is nonlinear to emphasize the relevant parts. It can also be observed that the signal arises slightly before stimulus onset. Rather than a detection error, this results from the effect of the filter on the interpolated signal, which replaced the stimulus artifact. DLR, dorso-lateral region; VMR, ventro-medial region.