Table 3.

F (with degrees of freedom) and P-values in two-way ANOVA test for experiments shown in Figures 1B, 2A,B, 3.

ANOVA	F (DFn, DFd)	P-value
Figure 1B
Interaction	F(4, 20) = 5.472	P = 0.0038
MOCK vs. IL33oe	F(1, 20) = 86.39	P < 0.0001
Vehicle vs. PAC-1	F(4, 20) = 10.42	P < 0.0001
Figure 2A
Interaction	F(2, 12) = 5.211	P = 0.0235
Scramble vs. IL33KD	F(1, 12) = 45.28	P < 0.0001
Vehicle vs. TMZ	F(2, 12) = 8.631	P = 0.0048
Figure 2B
γH2AX, 48 h
Interaction	F(1, 8) = 13.94	P = 0.0058
MOCK vs. IL33oe	F(1, 8) = 8.065	P = 0.0218
Vehicle vs. TMZ	F(1, 8) = 21.26	P = 0.0017
γH2AX, 72 h
Interaction	F(1, 8) = 48.21	P = 0.0001
MOCK vs. IL33oe	F(1, 8) = 47.28	P = 0.0001
Vehicle vs. TMZ	F(1, 8) = 625.8	P < 0.0001
Figure 3
IL33KD-48 h
Interaction	F(1, 8) = 0.01036	P = 0.9214
Scramble vs. IL33KD	F(1, 8) = 68.36	P < 0.0001
Vehicle vs. TMZ	F(1, 8) = 21.38	P = 0.0017
IL33KD-72 h
Interaction	F(1, 8) = 25.65	P = 0.0010
Scramble vs. IL33KD	F(1, 8) = 690	P < 0.0001
Vehicle vs. TMZ	F(1, 8) = 77.44	P < 0.0001
IL33oe-48 h
Interaction	F(1, 8) = 0.0004621	P = 0.9834
MOCK vs. IL33oe	F(1, 8) = 54.84	P < 0.0001
Vehicle vs. TMZ	F(1, 8) = 43.73	P = 0.0002
IL330e-72 h
Interaction	F(1, 8) = 17.38	P = 0.0031
MOCK vs. IL33oe	F(1, 8) = 107.5	P < 0.0001
Vehicle vs. TMZ	F(1, 8) = 33.58	P = 0.0004

IL-33, Interleukin-33; IL33oe, IL-33 overexpression; TMZ, temozolomide.