Figure 2.

Metaregression of mean testosterone on mean age for (A) all 11 cohort studies and (B) 9 studies with articles that were selected by systematic literature searches and screening. The size of plotted points refers are proportional to the inverse of the corresponding SEs (indicative of relative weightings), with lines demonstrating the fitted model and 95% CIs. Plotted estimates are numbered as from the following articles (cohort studies): 1=Srinath et al⁴⁸ (ARIC); 2=Chan et al³⁷ (BHS); 3=Hsu et al⁹ (CHAMP); 4=Shores et al⁵⁰ (CHS); 5=Lee et al⁴³ (EMAS); 6=Chan et al⁴¹ (HIMS); 7=Ohlsson et al⁴⁴ (MrOS Sweden); 8=Kische et al⁴⁶ (SHIP); 9=Sueoka et al⁵³ (MrOS USA); 10=Pencina et al⁵⁷ (FHS); 11=Li et al⁵⁶ (MAILES). *=includes articles from two additional studies (FHS, MAILES) that were not identified from systematic searches but by colleagues.