Table 1.

The system-initiated and user-initiated functionalities offered in the MyPal smartphone app

System-initiated functionality		Description
PS1	Physical symptom questionnaires	Notifications to complete physical symptom questionnaires are issued once per week.
PS2	Psychoemotional symptom questionnaires	Notifications to complete a psychoemotional symptom questionnaire are issued once per week.
PS3	Screener questionnaires	Notifications to complete a screener questionnaire concerning (1) the patient’s ongoing engagement with the MyPal Study, and (2) the risk of medication non-adherence. Responses will determine the motivational messages that patients will be receiving and the highest priority topics for the discussion guide presented to the HCP (issued at months 0, 3 and 6).
PS4	Motivational messages	Tailored short motivational messages presented to the patient. Their content is determined based on a custom algorithm that receives input from patient responses (issued twice weekly until week 4, then once weekly until week 24).
PS5	Medication reminders	Notifications that remind the patient to take their medication; determined by the patient via the medication management functionality.

User-initiated functionality		Description
PU1	Spontaneous symptom reporting	A form that is used by the patient to spontaneously report physical or psychoemotional symptoms in a structured or unstructured way.
PU2	Medication management	An editable list of the patient’s medication plan along with the dosage and the frequency of intake.
PU3	Personal health information recommender	A personalised search engine that retrieves health information related to health status of the patient.
PU4	Self-reported information review	A view that presents the patient’s past responses to physical and psychoemotional questionnaires.
PU5	Activity information review	A view that presents past daily step count and sleep quality indicators acquired by the commercial wristband.

HCP, healthcare provider.