Table 5.
Systemic rheumatic disease | Age (years) | 0–36 months of follow-up | >36 months of follow-up | ||||
HR (main effect) | HR (main effect) | ||||||
95% CI | P value | 95% CI | P value | ||||
RA | <50 | 0.43 | 0.28 to 0.69 | <0.001 | 1.36** | 0.72 to 2.59 | 0.345 |
≥50 | 0.63 | 0.60 to 0.67 | <0.001 | 1.12* | 1.04 to 1.21 | 0.002 | |
AS | <50 | 0.57 | 0.33 to 0.96 | 0.037 | 0.57 | 0.33 to 0.96 | 0.037 |
≥50 | 0.65 | 0.52 to 0.83 | <0.001 | 1.04** | 0.77 to 1.41 | 0.806 | |
PsA | <50 | 0.52 | 0.28 to 0.95 | 0.036 | 0.52 | 0.28 to 0.95 | 0.036 |
≥50 | 0.69 | 0.60 to 0.79 | <0.001 | 1.08* | 0.89 to 1.31 | 0.418 | |
SLE | <50 | 2.74 | 1.92 to 3.92 | <0.001 | 2.74 | 1.92 to 3.92 | <0.001 |
≥50 | 1.47 | 1.30 to 1.66 | <0.001 | 1.89* | 1.59 to 2.25 | <0.001 | |
SSc | <50 | 5.18 | 2.71 to 9.89 | <0.001 | 5.18 | 2.71 to 9.89 | <0.001 |
≥50 | 2.2 | 1.82 to 2.66 | <0.001 | 4.01** | 3.00 to 5.37 | <0.001 |
P value for interaction *<0.001; **<0.05.
AS, ankylosing spondylitis; PsA, psoriatic arthritis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SSc, systemic sclerosis.