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. 2021 Nov 2;7(3):e001694. doi: 10.1136/rmdopen-2021-001694

Table 5.

HR, with 95% CI and p values, for the effect of RA, AS, PSA, SLE and SSc on all-cause mortality of patients <50 years and ≥50 years of age for the first 3 years (0–36 months) and for the following 2 years (>36 months) of follow-up

Systemic rheumatic disease Age (years) 0–36 months of follow-up >36 months of follow-up
HR (main effect) HR (main effect)
95% CI P value 95% CI P value
RA <50 0.43 0.28 to 0.69 <0.001 1.36** 0.72 to 2.59 0.345
≥50 0.63 0.60 to 0.67 <0.001 1.12* 1.04 to 1.21 0.002
AS <50 0.57 0.33 to 0.96 0.037 0.57 0.33 to 0.96 0.037
≥50 0.65 0.52 to 0.83 <0.001 1.04** 0.77 to 1.41 0.806
PsA <50 0.52 0.28 to 0.95 0.036 0.52 0.28 to 0.95 0.036
≥50 0.69 0.60 to 0.79 <0.001 1.08* 0.89 to 1.31 0.418
SLE <50 2.74 1.92 to 3.92 <0.001 2.74 1.92 to 3.92 <0.001
≥50 1.47 1.30 to 1.66 <0.001 1.89* 1.59 to 2.25 <0.001
SSc <50 5.18 2.71 to 9.89 <0.001 5.18 2.71 to 9.89 <0.001
≥50 2.2 1.82 to 2.66 <0.001 4.01** 3.00 to 5.37 <0.001

P value for interaction *<0.001; **<0.05.

AS, ankylosing spondylitis; PsA, psoriatic arthritis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SSc, systemic sclerosis.