Table 5.
Univariable and multivariable analyses for admission to the ICU, on the day of intubation and in-hospital mortality.
Univariable analysis | Multivariable analysis | |||
---|---|---|---|---|
p value | OR (95% CI) | p value | OR (95% CI) | |
On admission to the ICU | ||||
Age | 0.007* | 1.036 (1.010-1.063) | - | - |
Platelet | 0.004* | 0.995 (0.991-0.998) | - | - |
C-reactive protein | 0.003* | 1.008 (1.003-1.014) | 0.001* | 1.009 (1.004-1.015) |
N/LP ratio | 0.678 | 1.000 (0.999-1.002) | 0.003* | 1.045 (1.015-1.075) |
On the day of intubation | ||||
Platelet | <0.001** | 0.994 (0.991-0.998) | - | - |
Neutrophil | <0.001** | 1.002 (1.001-1.004) | - | - |
MPV | 0.019* | 1.435 (1.062-1.938) | - | - |
Urea | <0.001** | 1.020 (1.010-1.031) | - | - |
C-reactive protein | <0.001** | 1.019 (1.011-1.027) | <0.001** | 1.017 (1.008-1.026) |
D-dimer | 0.002* | 1.001 (1.000-1.002) | - | - |
LDH | <0.001** | 1.002 (1.001-1.003) | 0.004* | 1.002 (1.001-1.004) |
N/LP ratio | <0.001** | 1.225 (1.110-1.351) | 0.010* | 1.139 (1.032-1.258) |
On the day of mortality | ||||
White blood cells count | 0.001* | 1.096 (1.038-1.156) | - | - |
Hemoglobin | <0.001** | 0.715 (0.599-0.855) | - | - |
Platelets | <0.001** | 0.992 (0.989-0.996) | - | - |
Neutrophil | <0.001** | 1.002 (1.001-1.004) | - | - |
MPV | <0.001** | 1.848 (1.357-2.518) | - | - |
Urea | <0.001** | 1.030 (1.019-1.042) | - | - |
Creatinine | 0.004* | 1.458 (1.124-1.890) | - | - |
AST | 0.013* | 1.015 (1.003-1.027) | - | - |
C-reactive protein | <0.001** | 1.031 (1.020-1.043) | 0.002* | 1.036 (1.013-1.059) |
D-dimer | <0.001** | 1.001 (1.000-1.001) | - | - |
Procalcitonin | <0.001** | 6.294 (2.597-15.255) | - | - |
LDH | <0.001** | 1.004 (1.003-1.006) | 0.001* | 1.006 (1.002-1.010) |
N/LP ratio | <0.001** | 1.375 (1.182-1.600) | 0.037* | 1.424 (1.021-1.985) |
All clinically relevant parameters were included in the model.
*p<0.05, **p<0.001
Abbreviations: OR: odds ratio; CI :confidence interval; ICU: intensive care unit; MPV: mean platelet volume; AST: aspartate aminotransferase; LDH: lactate dehydrogenase; N/LP: neutrophil to lymphocyte platelet ratio