Table 4. Association of 5-hmC expression score with clinicopathological features in EC.
5-hmC low | 5-hmC high | ||
---|---|---|---|
Characteristic | ≤80 | >80 | p-value |
Patients (n) | 46 | 40 | |
Age (years) | 0.459 | ||
Range | 31–79 | 33–88 | |
Mean ± SEM | 54.55 ± 1.64 | 56.37 ± 1.83 | |
FIGO stage (n [%]) | 1.000 | ||
I, II | 32 (53.3) | 28 (46.7) | |
III, IV | 14 (53.8) | 12 (46.2) | |
Nuclear grade (n [%]) | 0.895 | ||
G1 | 20 (51.3) | 19 (48.7) | |
G2 | 13 (56.5) | 10 (43.5) | |
G3 | 13 (54.2) | 11 (45.8) | |
Histological type (n [%]) | 0.509a | ||
CC | 3 (75.0) | 1 (25.0) | |
EmAC | 37 (51.4) | 35 (48.6) | |
MC | 0 (0.0) | 1 (100.0) | |
SC | 6 (66.7) | 3 (33.3) | |
Histological type (n [%]) | 0.971 | ||
Type I EC (EmAC G1 and G2) | 34 (54.8) | 28 (45.2) | |
Type II EC (EmAC G3, MC, CC, and SC) | 12 (50.0) | 12 (50.0) |
a Fisher’s exact test. CC, clear cell carcinoma; EmAC, endometrioid adenocarcinoma; MC, mucinous carcinoma; SC, serous carcinoma; SEM, standard error of mean.