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. 2021 Nov 3;16(11):e0259330. doi: 10.1371/journal.pone.0259330

Table 4. Association of 5-hmC expression score with clinicopathological features in EC.

5-hmC low 5-hmC high
Characteristic ≤80 >80 p-value
Patients (n) 46 40
Age (years) 0.459
Range 31–79 33–88
Mean ± SEM 54.55 ± 1.64 56.37 ± 1.83
FIGO stage (n [%]) 1.000
    I, II 32 (53.3) 28 (46.7)
    III, IV 14 (53.8) 12 (46.2)
Nuclear grade (n [%]) 0.895
    G1 20 (51.3) 19 (48.7)
    G2 13 (56.5) 10 (43.5)
    G3 13 (54.2) 11 (45.8)
Histological type (n [%]) 0.509a
    CC 3 (75.0) 1 (25.0)
    EmAC 37 (51.4) 35 (48.6)
    MC 0 (0.0) 1 (100.0)
    SC 6 (66.7) 3 (33.3)
Histological type (n [%]) 0.971
    Type I EC (EmAC G1 and G2) 34 (54.8) 28 (45.2)
    Type II EC (EmAC G3, MC, CC, and SC) 12 (50.0) 12 (50.0)

a Fisher’s exact test. CC, clear cell carcinoma; EmAC, endometrioid adenocarcinoma; MC, mucinous carcinoma; SC, serous carcinoma; SEM, standard error of mean.