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. 2021 Oct 22;17(10):e1009807. doi: 10.1371/journal.ppat.1009807

Fig 2. V2 NAb sensitivity of candidate strains.

Fig 2

A) MAb IC50s against candidate PVs bearing full-length wild-type (WT) gp160 spikes, except for WITO, AC10, 6101, KNH1144 and sc422, that were gp160ΔCT WT. For CH01 and VRC38, UCA sensitivities are shown. CH01 and PG9 NAb IC50s were measured against PVs bearing Envs with engineered glycans: GnT1- and B4GalT1+ST6Gal1 (abbreviated as B4G+ST6), respectively. GnT1- PV of strains BB201 and CNE58 strains were not infectious. B) CH01 IC30s and % maximum CH01 neutralization saturation in unmodified (left) and GnT1- (right) formats.