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. 2021 Nov 1;13(1):1981202. doi: 10.1080/19420862.2021.1981202

Figure 10.

Figure 10.

Projected human plasma concentration using PK data from cynomolgus monkeys. Predicted bemarituzumab plasma concentration-time profile (median [solid line], 5% and 95% quantiles [dashed lines], 90% prediction interval [shaded area]) in humans following 1 mg/kg IV administration. Bemarituzumab concentration-time profiles were scaled from cynomolgus monkey PK data using Dedrick approach with exponent of 0.85 and 1 for clearance and V1, respectively