Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 31;20(19):2021–2039. doi: 10.1080/15384101.2021.1965723

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

PMC Copyright notice

Figure 1. — The expression of circLNPEP in ovarian cancer and the stability of circLNPEP

(a-b) Overall survival and progression-free survival curves. Patients with high circLNPEP expression levels exhibited a poor prognosis.(c) CircLNPEP expression in ANT and cancer tissues was detected by qRT-PCR.P < 0.001. (D) CircLNPEP expression in human normal ovarian epithelial cell line and ovarian cancer cell lines was examined by qRT-PCR. (e) qRT-PCR analysis of circLNPEP and LNPEP mRNA after treatment with RNase R. (f-g) The abundance of circLNPEP and LNPEP mRNA was assessed by qRT-PCR treated with Actinomycin D at the indicated time points. Quantified values were expressed as mean ± standard deviation. Experiments were conducted independently in triplicate. GAPDH was used as internal control. ***P < 0.001 vs IOSE80 group. ^{^^^}P < 0.001 vs RNase R⁻ group. ^###P < 0.001 vs circLNPEP group.LNPEP: leucyl and cystinyl aminopeptidase. ANT: adjacent tissues. qRT-PCR: quantitative reverse transcription polymerase chain reaction. GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.