Fig. 1.

Chronic stress induced behavior alterations (A) A schematic showing the chronic social defeat stress paradigm. (B) Representative examples of the exploration traces of different groups revealed by the social interaction test. (C) Comparison of the relative time in the interaction/corner zone of different groups (n=15 mice for each group, *** p <0.001, ns, no significant difference). (D) Representative examples of the exploration traces of different groups revealed by the open field test. (E) Comparison of the relative time in the center/corner zone of different groups (n=15 mice for each group, *** p <0.001).