Serial transverse sections of the soleus muscles of rats in the control (WR; A–B), Goto-Kakizaki (GK; C–D), and exercised Goto-Kakizaki (GK-Ex; E–H) groups stained for ATPase activity after preincubation at pH 10.4 (A, C, E, and G) and pH 4.5 (B, D, F, and H). In the GK-Ex group, the soleus muscles in seven rats contained only type I fibers (E, F), whereas these muscles in three rats contained three fiber types (G, H). 1, type I; 2, type IIA; 3, type IIC. Scale bar=200 μm.