(c).
SPINA-GT | TSHI | TTSI | ||||
---|---|---|---|---|---|---|
Metformin | Nonmetformin | Metformin | Nonmetformin | Metformin | Nonmetformin | |
MMP | 0.014 (-0.025, 0.053) | 0.025 (-0.022, 0.072) | -0.018 (-0.083, 0.046) | -0.034 (-0.094, 0.026) | -0.018 (-0.079, 0.043) | -0.042 (-0.103, 0.019) |
MEP | 0.003 (-0.025, 0.031) | 0.003 (-0.022, 0.029) | -0.043 (-0.088, 0.003) | 0.021 (-0.011, 0.054) | -0.030 (-0.074, 0.013) | 0.010 (-0.023, 0.043) |
MiBP | -0.001 (-0.068, 0.066) | 0.014 (-0.051, 0.080) | -0.038 (-0.148, 0.073) | 0.008 (-0.075, 0.092) | -0.027 (-0.132, 0.077) | -0.002 (-0.087, 0.083) |
MnBP | 0.010 (-0.051, 0.070) | -0.010 (-0.067, 0.048) | -0.068 (-0.168, 0.032) | 0.018 (-0.055, 0.091) | -0.057 (-0.152, 0.038) | 0.024 (-0.051, 0.098) |
MBzP | 0.018 (-0.023, 0.059) | -0.008 (-0.048, 0.031) | 0.029 (-0.039, 0.096) | 0.002 (-0.049, 0.052) | 0.018 (-0.046, 0.083) | 0.010 (-0.042, 0.061) |
MCPP | 0.005 (-0.017, 0.028) | -0.016 (-0.040, 0.008) | 0.009 (-0.028, 0.047) | 0.003 (-0.027, 0.034) | 0.003 (-0.032, 0.039) | 0.008 (-0.023, 0.039) |
MiNP | 0.029 (-0.027, 0.084) | 0.044 (-0.011, 0.099) | -0.111 (-0.201, -0.021)∗ | -0.030 (-0.100, 0.041) | -0.088 (-0.173, -0.002)∗ | -0.039 (-0.111, 0.032) |
MCHP | 0.014 (-0.006, 0.034) | -0.001 (-0.023, 0.021) | -0.018 (-0.051, 0.015) | 0.005 (-0.023, 0.033) | -0.018 (-0.049, 0.014) | 0.007 (-0.021, 0.036) |
MEHP | -0.004 (-0.027, 0.019) | 0.032 (0.009, 0.056)∗∗ | 0.003 (-0.035, 0.041) | -0.025 (-0.055, 0.006) | 0.006 (-0.030, 0.042) | -0.034 (-0.065, -0.003)∗ |
MECPP | 0.019 (-0.037, 0.074) | 0.035 (-0.015, 0.085) | -0.096 (-0.188, -0.005)∗ | -0.026 (-0.090, 0.038) | -0.069 (-0.155, 0.018) | -0.029 (-0.094, 0.036) |
MEHHP | 0.033 (-0.021, 0.086) | 0.047 (-0.009, 0.103) | -0.121 (-0.209, -0.034)∗∗ | -0.046 (-0.117, 0.025) | -0.095 (-0.179, -0.011)∗ | -0.053 (-0.125, 0.019) |
MEOHP | 0.022 (-0.026, 0.071) | 0.029 (-0.013, 0.070) | -0.096 (-0.175, -0.016)∗ | -0.048 (-0.101, 0.005) | -0.076 (-0.152, -0.001)∗ | -0.042 (-0.096, 0.012) |
MCMHP | 0.019 (-0.026, 0.065) | 0.038 (-0.010, 0.086) | -0.100 (-0.175, -0.026)∗∗ | -0.028 (-0.089, 0.034) | -0.072 (-0.143, -0.001)∗ | -0.035 (-0.098, 0.027) |
In the multiple regression analysis, age, sex, BMI, current smoking status, and UIC were adjusted. Urinary concentrations of phthalate metabolites and UIC were corrected by urine Cr and ln-transformed to approximate a normal distribution. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.