Table 2.
Operative indications and details
| Variable | Overall (n = 212) | 1990–1999 (n = 75) | 2000–2009 (n = 73) | 2010–2016 (n = 64) | P-value |
|---|---|---|---|---|---|
| Indications for surgery | |||||
| Medically intractable disease (acute or chronic) | 176 (83.0) | 63 (84.0) | 56 (76.7) | 57 (89.1) | 0.1534 |
| Toxic megacolon | 6 (2.8) | 1 (1.3) | 3 (4.1) | 1 (1.6) | |
| Perforation | 7 (3.3) | 3 (4.0) | 3 (4.1) | 1 (1.6) | |
| Acute hemorrhage | 2 (0.9) | 1 (1.3) | 1 (1.4) | 0 (0) | |
| Dysplasia | 12 (5.7) | 5 (6.7) | 4 (5.5) | 3 (4.7) | |
| Carcinoma | 3 (1.4) | 1 (1.3) | 2 (2.7) | 0 (0) | |
| Other | 6 (2.8) | 1 (1.3) | 3 (4.1) | 2 (3.1) | |
| All acute surgery | 103 (48.6) | 25 (33.3) | 40 (54.8) | 38 (59.4) | 0.0036 |
| Age at colectomy (yr) | 36 (26–47) | 35 (24–49) | 39 (28–47) | 34 (25–45) | 0.7023 |
| Age at IPAA (yr) | 37 (27–48) | 35 (26–48) | 39 (29–50) | 34 (26–46) | 0.5313 |
| Surgery | 0.00012 | ||||
| 1-Stage | 22 (10.4) | 11 (14.7) | 7 (9.6) | 4 (6.3) | |
| Traditional 2-stagea | 55 (25.9) | 34 (45.3) | 16 (21.9) | 5 (7.8) | |
| Modified 2-stageb | 78 (36.8) | 17 (22.7) | 20 (27.4) | 41 (64.1) | |
| 3-Stage | 57 (26.9) | 13 (17.3) | 30 (41.1) | 14 (21.9) | |
| Laparoscopic technique | 45 (21.2) | 0 (0) | 16 (21.9) | 29 (45.3) | < 0.00001 |
| Loop ileostomy formation | 111 (52.4) | 48 (64.0) | 47 (64.4) | 19 (29.7) | 0.00002 |
| Pouch configuration | < 0.00001 | ||||
| J pouch | 152 (71.7) | 42 (56.0) | 46 (63.0) | 64 (100) | |
| W pouch | 60 (28.3) | 33 (44.0) | 27 (37.0) | 0 | |
| Stapled IPAA | 185 (87.3) | 51 (68.0) | 70 (95.9) | 64 (100) | < 0.00001 |
| Surgery duration (min) | 251 (210–294) | 215 (180–251) | 256 (212–304) | 267 (236–330) | < 0.00001 |
| Length of hospital stay (day) | 9 (8–13) | 10 (8–13) | 9 (8–12) | 9 (7–12) | 0.3296 |
Values are presented as number (%) and median (interquartile range).
IPAA, ileal pouch-anal anastomosis.
a
Restorative proctocolectomy/IPAA with ileostomy then ileostomy closure;
b
colectomy with ileostomy then proctectomy with IPAA.