Fig. 1.

Time to first enthesitis resolution through week 52 in PsA patients with enthesitis at baseline

Observed resolution status pooled across DISCOVER-1 and DISCOVER-2. The intersections of the dashed lines represent the time points at which 50% of patients achieved resolution of enthesitis in the Q4W and Q8W groups (week 16) and in the placebo-crossover group (week 24). Enthesitis defined as LEI EC ≥ 1; enthesitis resolution defined as LEI EC = 0. Patients ‘at risk’ at each visit are those still with enthesitis. GUS: guselkumab; EC: enthesitis count; LEI: Leeds Enthesitis Index; PBO, placebo; Q4W/Q8W: every 4/8 weeks.