Table 2.
RA | Matched controls | |||
---|---|---|---|---|
n = 1366 | n = 6995 | OR (95% CI) | P-value | |
ADP-inhibitor | 827 (60.5%) | 4288 (61.3%) | 0.96 (0.85, 1.09) | 0.521 |
Anticoagulant | 205 (15.0%) | 1067 (15.3%) | 1.00 (0.84, 1.18) | 0.957 |
Antidiabetic | 231 (16.9%) | 1260 (18.0%) | 0.91 (0.78, 1.07) | 0.251 |
Insulin | 111 (8.1%) | 587 (8.4%) | 0.98 (0.79, 1.22) | 0.832 |
Non-insulin | 151 (11.1%) | 873 (12.5%) | 0.84 (0.70, 1.02) | 0.071 |
ACEi or ARB | 855 (62.6%) | 4561 (65.2%) | 0.91 (0.80, 1.03) | 0.117 |
Aldosterone antagonist | 59 (4.3%) | 277 (4.0%) | 1.10 (0.82, 1.48) | 0.509 |
Antiarrhythmic | 11 (0.8%) | 90 (1.3%) | 0.65 (.0.34, 1.23) | 0.187 |
Beta-blocker | 1147 (84.0%) | 5764 (82.4%) | 1.11 (0.94, 1.30) | 0.217 |
Ca-blocker | 253 (18.5%) | 1310 (18.7%) | 0.97 (0.84, 1.14) | 0.739 |
Digitalis | 62 (4.5%) | 307 (4.4%) | 1.04 (0.78, 1.38) | 0.788 |
Diuretic | 634 (46.4%) | 3176 (45.4%) | 1.06 (0.94, 1.19) | 0.351 |
Ezetimibe | 28 (2.1%) | 166 (2.4%) | 0.86 (0.57, 1.30) | 0.463 |
Nitrate | 960 (70.3%) | 4863 (69.5%) | 1.03 (0.91, 1.17) | 0.651 |
Statin | 998 (73.1%) | 5410 (77.3%) | 0.79 (0.69, 0.91) | 0.001 |
Intensity of statin therapy | 0.281 | |||
Low | 49 (4.9%) | 311 (5.8%) | ||
Moderate | 804 (80.6%) | 4272 (79.0%) | ||
High | 145 (14.5%) | 827 (15.3%) |
ACEi: angiotensin-converting-enzyme inhibitor; ADP: adenosine diphosphate; ARB: angiotensin receptor blocker; OR: odds ratio.