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. 2021 Sep 22;599(7883):158–164. doi: 10.1038/s41586-021-03935-z

Extended Data Fig. 7. Influence of Kv4.2–KChIP1 interface mutations on KChIP1 modulation of activation and inactivation.

Extended Data Fig. 7

a. Normalized and superposed current traces of WT with (black) or without (gray) KChIP1 elicited by test pulses of 40 mV for the qualitative comparisons of inactivation kinetics (n = 8 independent experiments). b–e. Peak conductance-Voltage (Gp-V) relationships of WT with (black circle) or without (white circle) KChIP1, and each mutant with (coloured symbol) or without (coloured open symbol) KChIP1 obtained from Supplementary Fig. 5a. Symbols and bars represent means ± s.e.m. (n = 8). f–i. Comparison of the voltage-dependent prepulse inactivation for WT with (black circle) or without (white circle) KChIP1, and each mutant with (coloured symbol) or without (coloured open symbol) KChIP1 obtained from Supplementary Fig. 5c.