Table 3.

Multivariable Cox regression models examining the independent associations of neutropenia

	HR (95% CI), P-value
	Model 1	Model 2	Model 3	Model 4	Model 5
Serology positive	1.89 (1.26, 2.82), P = 0.001
ESR ≥ 25	1.71 (1.23, 2.35), P = 0.001	1.63 (1.17, 2.28), P = 0.004	1.68 (1.21, 2.35), P = 0.002	1.69 (1.22, 2.38), P = 0.002	1.62 (1.40, 1.87), P = 0.004
AM use	1.80 (1.28, 2.68), P = 0.005	1.89 (1.26, 2.82), P = 0.002	1.89 (1.27, 2.83), P = 0.002	1.89 (1.27, 2.82), P = 0.002	1.89 (1.26, 2.83), P = 0.002
SLEDAI-2K score		1.03 (0.99, 1.06), P = 0.138
SLEDAI-2K modifieda			0.99 (0.96, 1.03), P = 0.8
SLEDAI-2K ≥ 6				0.87 (0.60, 1.24), P = 0.4
In LLDAS					0.56 (0.42, 0.74), P < 0.001

^aSLEDAI-2K modified excludes leucopenia. AM: anti-malarials; LLDAS: lupus low disease activity state.