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. 2021 May 4;91(6):1374–1382. doi: 10.1038/s41390-021-01525-3

Fig. 2. Case demonstration of how cerebral autoregulation was assessed in one piglet.

Fig. 2

The assessment used temporal measurements of MAP (b) and rCBF (c) during modulation of CPB flow (a). A 45-s moving window with maximal overlap was used to sample the data. For each window, the absolute change (maximum-minimum) in MAP (ΔMAP, d), and the Pearson correlation between MAP and rCBF (r, e) were calculated. The set of correlation coefficients for which ΔMAP exceeded 2 mmHg were then Fisher-transformed, and the hyperbolic tangent of their average returned a single LDx value for the assessment (f). In this piglet, rCBF was overall uncorrelated with MAP, resulting in an LDx of 0.1.