Table 4.
Intra- and post-intervention clinical variables (presented as means and standard deviations or medians and interquartile ranges) for the different perfusion strategies.
| Variable | DH-CPB (n = 7) |
SCP (n = 7) |
DHCA (n = 7) |
Control (n = 4) |
p value |
|---|---|---|---|---|---|
| Intra-intervention relative cerebral blood Flow (%) | 63 [40, 70] | 35 [17, 38] | 5 [4, 13] | 75 [62, 93] | 0.02 |
| Changes in intracranial temperature (°C) | −1.3 ± 1.1 | −1.7 ± 2.3 | −0.7 ± 3.0 | N/A | 0.31 |
| Changes in arterial pCO2 (mmHg) | 4.3 ± 18.0 | 2.7 ± 10.1 | −5.1 ± 8.1 | −6.2 ± 6.7 | 0.82 |
| Post-intervention mean arterial pressure (mmHg) | 63.7 ± 22.9 | 56.0 ± 6.6 | 75.4 ± 9.9 | 58.1 ± 6.4 | 0.08 |
| Post-intervention pH | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.1 | 7.4 ± 0.0 | 0.70 |
| Post-intervention Arterial pO2 (mmHg) | 280 [140, 330] | 230 [130, 250] | 230 [170, 300] | 280 [260, 320] | 0.52 |
| Post-intervention arterial pCO2 (mmHg) | 45.7 ± 17.9 | 41.9 ± 7.7 | 39.6 ± 6.9 | 39.7 ± 3.4 | 0.73 |
| Post-intervention arterial lactate (mM) | 5.1 ± 1.7 | 6.7 ± 1.2 | 6.9 ± 1.8 | 6.0 ± 1.2 | 0.13 |
| Post-intervention hematocrit (%) | 35.3 ± 3.9 | 37.0 ± 4.3 | 33.7 ± 5.0 | 30.8 ± 4.4 | 0.17 |
| Post-intervention intracranial temperature (°C) | 33.3 ± 2.7 | 34.4 ± 2.2 | 35.5 ± 2.5 | 36.3 ± 1.7 | 0.20 |
Relative cerebral blood flow during the intervention was significantly different between groups.