Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 3;7:331. doi: 10.1038/s41420-021-00663-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 9 — Differentially expressed proteins of LAMC2 in normal (A) and pancreatic cancer tissues (B) in the Human Protein Atlas database. Differentially expressed proteins of HMGA1 in normal (C) and pancreatic cancer tissues (D) in the Human Protein Atlas database. Differentially expressed proteins of CSTB in normal (E) and pancreatic cancer tissues (F) in the Human Protein Atlas database. G LAMC2 were overexpressed in metastatic cell lines relative to primary cell lines. H HMGA1were overexpressed in metastatic cell lines relative to primary cell lines. I CSTB were overexpressed in metastatic cell lines relative to primary cell lines. Enrichment of metastatic-related signaling pathways in primary/metastatic tumor samples. J Relative expression levels of hub genes in metastatic-related signaling pathways were upregulated in metastatic lesions compared with primary samples. K GSVA enrichment analysis showing the activation states of biological pathways in primary/metastatic PDAC samples. The heatmap was used to visualize these biological processes, and yellow represented activated pathways and blue represented inhibited pathways.