Table 1.
Genome segment | Missense mutation | Synonymous mutation | Frameshift deletion/in frame del | Other mutation | |||
---|---|---|---|---|---|---|---|
Upstream | downstream | Stop gained | |||||
ORF1ab | 344 | 306 | 8 | 14 | 0 | 2 | 674 |
S | 94 | 57 | 0 | 0 | 25 | 1 | 177 |
E | 8 | 4 | 1 | 2 | 0 | 0 | 15 |
M | 9 | 13 | 0 | 1 | 0 | 0 | 23 |
N (87) | 57 | 26 | 1 | 3 | 0 | 0 | 87 |
ORF8 | 20 | 4 | 3 | 2 | 0 | 3 | 32 |
ORF10 | 5 | 1 | 2 | 0 | 0 | 0 | 8 |
ORF 3a | 48 | 15 | 0 | 0 | 0 | 0 | 63 |
ORF6 | 3 | 2 | 0 | 0 | 0 | 1 | 6 |
ORF7a | 16 | 3 | 0 | 1 | 0 | 0 | 20 |
ORF7b | 9 | 0 | 0 | 0 | 0 | 1 | 10 |
Total | 613 | 431 | 15 | 23 | 25 | 8 | 1115 |
E: envelope protein; M: membrane glycoprotein; N: Nucleocapsid phosphoprotein; ORF: open reading frame; S: spike glycoprotein; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2.