Table 2.
The top Frequent Mutations in Egypt and in the world during the second waves.
| Position | Ref | Obs | Egy. Freq (n = 183) | Wolrd Freq (n = 371822) | 1stWave EgyFreq (n = 265) | Gene | Transcription Pos | AA_change | Type of mutation |
|---|---|---|---|---|---|---|---|---|---|
| 23403 | A | G | 96.17% | 93.26% | 86.04% | S | c.1841A > G | D614G | Missense mutation |
| 14408 | C | T | 93.99% | 92.86% | 61.13% | ORF1ab | c.14144C > T | P4715L | Missense mutation |
| 3037 | C | T | 92.35% | 92.87% | 81.51% | ORF1ab | c.2772C > T | F924F | Synonymous mutation |
| 241 | C | T | 89.07% | 90.51% | 81.89% | ORF1ab | c.-25C > T | Upstream | Upstream mutation |
| 23731 | C | T | 72.68% | 02.18% | 12.83% | S | c.2169C > T | T723T | Synonymous mutation |
| 10097 | G | A | 71.58% | 02.17% | 14.72% | ORF1ab | c.9832G > A | G3278S | Missense mutation |
| 13536 | C | T | 69.95% | 01.36% | 12.83% | ORF1ab | c.13272C > T | Y4424Y | Synonymous mutation |
| 28908 | G | T | 68.31% | 00.07% | 12.45% | N | c.635G > T | G212V | Missense mutation |
| 4002 | C | T | 67.21% | 01.30 | 12.83% | ORF1ab | c.3737C > T | T1246I | Missense mutation |
| 28881 | GGG | AAC | 63.39% | 34.16% | 0.00% | N | c.608_610delGGGinsAAC | RG203KR | Missense mutation |
| 12534 | C | T | 55.74% | 00.15% | 12.45% | ORF1ab | c.12269C > T | T4090I | Missense mutation |
| 23593 | G | T | 55.19% | 00.39% | 13.58% | S | c.2031G > T | Q677H | Missense mutation |