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. 2021 Nov 3;11:21568. doi: 10.1038/s41598-021-00428-x

Table 1.

General characteristics of participants.

Characteristics Total participants COVID-19 participants
COVID-19 Control P-value Severe morbidity Mild morbidity P-value
Total number (n, %) 8,070 (100.0) 32,280 (100.0) 569 (100.0) 7,501 (100.0)
Age (years old) (n, %) 1.000  < 0.001*
0–9 81 (1.0) 324 (1.0) 6 (1.1) 75 (1.0)
10–19 276 (3.4) 1,104 (3.4) 6 (1.1) 270 (3.6)
20–29 2,057 (25.5) 8,228 (25.5) 31 (5.5) 2,026 (27.0)
30–39 832 (10.3) 3,328 (10.3) 25 (4.4) 807 (10.8)
40–49 1,036 (12.8) 4,144 (12.8) 30 (5.3) 1,006 (13.4)
50–59 1,567 (19.4) 6,268 (19.4) 71 (12.5) 1,496 (19.9)
60–69 1,199 (14.9) 4,796 (14.9) 116 (20.4) 1,083 (14.4)
70–79 617 (7.7) 2,468 (7.7) 118 (20.7) 499 (6.7)
80 +  405 (5.0) 1,620 (5.0) 166 (29.2) 239 (3.2)
Sex (n, %) 1.000  < 0.001*
Male 3,236 (40.1) 12,944 (40.1) 306 (53.8) 2,930 (39.1)
Female 4,834 (59.9) 19,336 (59.9) 263 (46.2) 4,571 (60.9)
Income (n, %) 1.000  < 0.001*
1 (low) 2,836 (35.1) 11,344 (35.1) 185 (32.5) 2,651 (35.3)
2 3,325 (41.2) 13,300 (41.2) 211 (37.1) 3,114 (41.5)
3 (high) 1,909 (23.7) 7,636 (23.7) 173 (30.4) 1,736 (23.1)
CCI score (n, %)  < 0.001*  < 0.001*
0 6,518 (80.8) 29,539 (91.5) 264 (46.4) 6,254 (83.4)
1 889 (11.0) 1,416 (4.4) 134 (23.6) 755 (10.1)
 ≥ 2 663 (8.2) 1,325 (4.1) 171 (30.1) 492 (6.6)
Asthma (n, %) 704 (8.7) 2,613 (8.1) 0.066 86 (15.1) 618 (8.2)  < 0.001*
COPD (n, %) 264 (3.3) 883 (2.7) 0.001* 55 (9.7) 209 (2.8)  < 0.001*
Hypertension (n, %) 1,657 (20.5) 6,428 (19.9) 0.214 275 (48.3) 1,382 (18.4)  < 0.001*
Previous 1–14 days (n, %)
Influenza 27 (0.3) 20 (0.1)  < 0.001* 6 (1.1) 21 (0.3) 0.003*
URI 1,442 (17.9) 1,003 (3.1)  < 0.001* 108 (19.0) 1,333 (17.8) 0.506
Previous 1–30 days (n, %)
Influenza 32 (0.4) 48 (0.2)  < 0.001* 7 (1.2) 25 (0.3) 0.006*
URI 1,741 (21.6) 1,741 (5.4)  < 0.001* 119 (20.9) 1,622 (21.6) 0.691
Previous 1–90 days (n, %)
Influenza 146 (1.8) 229 (0.7)  < 0.001* 14 (2.5) 132 (1.8) 0.227
URI 2,694 (33.4) 5,130 (15.9)  < 0.001* 177 (31.1) 2,517 (33.6) 0.233

CCI, Charlson comorbidity index; COPD, chronic obstructive pulmonary disease; upper respiratory tract infection, URI; COVID-19, coronavirus disease 2019; SD, standard deviation.

*Chi-square or Fisher's exact test. Significance at P < 0.05.

Independent t test. Significance at P < 0.05.