Table 3.
Crude and adjusted odds ratios of influenza and URI (previous 1–14, 1–30, and 1–90 days) for morbidity in COVID-19 participants.
| Characteristics | Severe participants | Mild participants | ORs (95% confidence interval) for morbidity | E-value (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|
| (exposure/total, %) | (exposure/total, %) | Crude | P-value | Model 1† | P-value | Model 2†‡ | P-value | ||
| Previous 1–14 days | |||||||||
| Influenza | 6/569 (1.1%) | 21/7,501 (0.3%) | 3.77 (1.68–8.80) | < 0.001* | 3.89 (1.93–10.01) | < 0.001* | 3.64 (1.55–9.21) | 0.001* | 6.74 (2.47–17.91) |
| URI | 108/569 (19.0%) | 1,333/7,501 (17.8%) | 1.10 (0.88–1.36) | 0.406 | 1.43 (1.13–1.81) | 0.003* | 1.40 (1.11–1.78) | 0.005* | 2.15 (1.46–2.96) |
| Previous 1–30 days | |||||||||
| Influenza | 7/569 (1.2%) | 25/7,501 (0.3%) | 3.73 (1.60–8.65) | 0.002* | 3.82 (1.53–9.55) | 0.004* | 3.59 (1.42–9.05) | 0.007* | 6.64 (2.19–17.59) |
| URI | 119/569 (20.9%) | 1,622/7,501 (21.6%) | 0.96 (0.78–1.18) | 0.692 | 1.30 (1.03–1.64) | 0.025* | 1.28 (1.02–1.61) | 0.037* | 1.88 (1.16–2.60) |
| Previous 1–90 days | |||||||||
| Influenza | 14/569 (2.5%) | 132/7,501 (1.8%) | 1.41 (0.81–2.46) | 0.227 | 1.57 (0.86–2.89) | 0.144 | 1.54 (0.84–2.84) | 0.162 | 1.00 (1.00–5.13) |
| URI | 177/569 (31.1%) | 2,517/7,501 (33.6%) | 0.89 (0.74–1.08) | 0.233 | 1.17 (0.96–1.44) | 0.124 | 1.17 (0.95–1.43) | 0.137 | 1.00 (1.00–2.21) |
*Unconditional logistic regression model, Significance at P < 0.05.
†Model 1 was adjusted for age, sex, income, CCI scores, asthma, COPD, and hypertension.
‡Model 2 was adjusted for model 1 plus influenza and URI.