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. 2021 Nov 3;11:21616. doi: 10.1038/s41598-021-01114-8

Table 1.

Conventional US characteristics of thyroid nodules.

Characteristics Benign Malignant
Nodules (n = 356) 84 272
Maximum diameter
≤ 1 cm 44 176
1–2 cm 23 68
≥ 2 cm 17 28
Location
Superior pole 7 56
Middle 53 124
Inferior pole 24 96
Aspect ratio
> 1 6 166
< 1 78 106
Echogenicity
Hypoechoic 29 258
Isoechoic or Mixed echoic 55 14
Calcification
None 69 124
Microcalcification 10 120
Macrocalcification 5 28
Color Doppler character*
Absent vascularity 32 137
Minimal vascularity 17 82
Moderate vascularity 20 35
Marked vascularity 15 18

*Color Doppler character was graded to be absent, minimal, moderate and marked. Absent vascularity: no vessel; minimal vascularity: point strip blood flow at 1–2 points, and the diameter of vessel was less than 1 mm; moderate vascularity: one vessel which diameter exceeded the radius of the lesion, or 3–4 point strip blood flow; marked vascularity: more than 4 vessels.