Table 3.
SARS-CoV-2 IgG seropositivity by self-reported clinical characteristics.
| IgG seropositivity | Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|---|
| % | (95% CI) | OR | 95% CI | P-value | OR | 95% CI | P-value3 | ||
| PCR status | Never done | 29.28 | (24.48–33.99) | 1 | < 0.0012 | 1 | |||
| Negative | 42.42 | (25.48–60.78) | 1.78 | 0.86 to 3.67 | 1.52 | 0.53 to 4.33 | 0.432 | ||
| Positive | 92.31 | (63.97–99.81) | 29.98 | 3.72 to 225.50 | 21.97 | 1.91 to 252.92 | 0.013 | ||
|
Contact with confirmed case |
No contact | 24.74 | (18.42–31.89) | 1 | < 0.0012 | 1 | |||
| Household member | 48.15 | (39.47–56.41) | 2.83 | 1.74 to 4.60 | 4.26 | 2.19 to 8.30 | < 0.001 | ||
| Non-cohabitating | 29.86 | (22.53–38.04) | 1.30 | 0.79 to 2.14 | 1.69 | 0.83 to 3.41 | 0.146 | ||
| COVID-19 symptoms | No | 14.60 | (9.15–21.64) | 1 | 1 | ||||
| Yes | 41.99 | (36.45–47.68) | 4.29 | 2.54 to 7.26 | < 0.0011 | 1.052 | 0.12 to 85.71 | 0.982 | |
| Type of symptoms | Ageusia/Anosmia | 77.36 | (68.21–84.92) | 13.57 | 8.02 to 22.96 | < 0.0011 | 15.30 | 5.98 to 39.12 | < 0.001 |
| Pneumonia diagn.$ | 75.00 | (47.62–92.73) | 6.35 | 2.01 to 20.03 | 0.0011 | 1.84 | 0.32 to 10.48 | 0.492 | |
| Cutaneous | 63.33 | (43.86–80.07) | 3.76 | 1.74 to 8.12 | < 0.0011 | 1.53 | 0.46 to 5.06 | 0.483 | |
| Fever | 47.51 | (40.06–55.05) | 2.83 | 1.89 to 4.23 | < 0.0011 | 1.59 | 0.75 to 3.36 | 0.225 | |
| GI symptoms | 50.47 | (40.63–60.23) | 2.57 | 1.65 to 4.02 | < 0.0011 | 1.44 | 0.69 to 3.01 | 0.325 | |
| Asthenia | 44.51 | (36.97–52.24) | 2.19 | 1.47 to 3.27 | 0.0121 | 1.52 | 0.67 to 3.45 | 0.311 | |
| Dyspnea | 47.06 | (34.83–59.55) | 1.96 | 1.16 to 3.30 | 0.0041 | 0.62 | 0.23 to 1.70 | 0.355 | |
| Cough | 42.67 | (34.64–50.99) | 1.84 | 1.22 to 2.78 | 0.0081 | 0.99 | 0.47 to 2.10 | 0.981 | |
| Myalgia | 42.47 | (34.93–50.51) | 1.78 | 1.18 to 2.68 | 0.0181 | 0.66 | 0.30 to 1.47 | 0.309 | |
| Headache | 40.46 | (33.08–48.18) | 1.64 | 1.10 to 2.44 | 0.7351 | 1.02 | 0.48 to 2.15 | 0.956 | |
| Odynophagia | 32.20 | (23.90–41.43) | 0.92 | 0.59 to 1.43 | < 0.0011 | 0.34 | 0.16 to 0.69 | 0.003 | |
| Number of symptoms | 0 | 14.60 | (9.15–21.64) | 1 | < 0.0012 | 1 | |||
| 1–3 | 32.59 | (24.78–41.19) | 2.83 | 1.56 to 5.13 | 1.82 | 0.45 to 71.96 | 0.751 | ||
| 4–6 | 38.79 | (29.89–48.29) | 3.71 | 2.03 to 6.78 | 1.55 | 0.10 to 25.34 | 0.760 | ||
| 7–9 | 70.00 | (55.39–82.14) | 13.65 | 6.33 to 29.45 | 2.47 | 0.27 to 22.31 | 0.421 | ||
| ≥ 10 | 63.64 | (30.79–89.07) | 10.24 | 2.74 to 38.21 | 7.46 | 1.74 to 32.03 | 0.007 | ||
$diagnosis.
1Fisher’s exact test.
2Chi-square test.
3Enter multivariate logistic regression. Variables significantly associated with seropositivity are highlighted in bold.
OR, Odds Ratio. 95% CI, 95% Confidence interval. GI, Gastrointestinal.