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. 2021 Oct 21;12:682082. doi: 10.3389/fgene.2021.682082

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Copyright © 2021 Wang, Ge, Zhang, Ye, Zhou, Li, Yan, Wu, Bai, Li, Zhu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical prognostic analysis of the five ferroptosis-related lncRNA models. (A) Relative expression of five ferroptosis-related lncRNAs in HCC patients at different clinical stages. (B) Relative expression of five lncRNAs in various cancer grades. (C) 3D-PCA plot of HCC patients divided into high- and low-risk groups based on gene expression (all genes). (D) 3D-PCA plot of HCC patients divided into high- and low-risk groups based on the expression of the five ferroptosis-related lncRNAs. (E) 2D-PCA plot of patients based on the expression of the five ferroptosis-related lncRNAs. (F) t-SNE plot of patients. lncRNA: long non-coding RNA; 3D/2D: three/two dimensional; PCA: principal component analysis.