Table 3.
Postoperative relevant clinical indicators with dialysis-dependent acute kidney injury after cardiac surgery.
| Factors | Survival group | Death group | t /χ2/ z | P |
|---|---|---|---|---|
| (n = 36) | (n = 54) | |||
| Hypoxemia, n (%) | 15 (41.7) | 24 (44.4) | 0.068 | 0.794 |
| Pulmonary infection, n (%) | 13 (36.1) | 29 (53.7) | 2.686 | 0.101 |
| Hemorrhage, n (%) | 8 (22.2) | 27 (50) | 7.013 | 0.008* |
| LCOS, n (%) | 18 (50.0) | 39 (72.2) | 4.593 | 0.032* |
| Septicemia, n (%) | 1 (2.8) | 6 (11.1) | 2.091 | 0.148 |
| Re-exploration, n (%) | 2 (5.6) | 7 (13.0) | 1.317 | 0.251 |
| IABP, n (%) | 4 (11.1) | 10 (18.5) | 0.902 | 0.342 |
| Duration of mechanical ventilation, days | 6.33 ± 10.16 | 5.64 ± 6.21 | 0.398 | 0.692 |
| Duration of RRT support, days | 8.91 ± 7.75 | 8.57 ± 8.62 | 0.189 | 0.850 |
| End of surgery to time of RRT, days | 3.83 ± 4.74 | 5.51 ± 6.65 | 1.306 | 0.195 |
| AKI to RRT time, h | 65.81 ± 91.94 | 99.78 ± 151.62 | 1.204 | 0.232 |
| Postoperative RBC transfusion, U | 11.36 ± 7.25 | 14.13 ± 11.81 | 1.256 | 0.212 |
| Postoperative infusion of plasma, ml | 2063.9 ± 2010.2 | 2840.3 ± 2994.6 | 1.363 | 0.176 |
| Surgical approach | ||||
| Valve replacement, n (%) | 19 (52.8) | 38 (70.4) | 0.064 | |
| Valve replacement + bypass, n (%) | 2 (5.6) | 7 (13.0) | ||
| Bypass, n (%) | 2 (5.6) | 2 (3.7) | ||
| Aortic surgery, n (%) | 12 (33.3) | 7 (13.0) | ||
| Other procedures, n (%) | 1 (2.8) | 0 (0) | ||
| AKI grading | ||||
| Grade 1, n (%) | 4 (11.4) | 10 (18.5) | 0.448 | |
| Grade 2, n (%) | 10 (27.8) | 10 (18.5) | ||
| Grade 3, n (%) | 22 (61.1) | 34 (63.0) | ||
| Anticoagulation modality | ||||
| No anticoagulation, n (%) | 19 (52.8) | 28 (51.9) | 0.636 | |
| Heparin, n (%) | 6 (16.7) | 13 (24.1) | ||
| Sodium citrate, n (%) | 11 (30.6) | 13 (24.1) | ||
| Pattern | ||||
| CRRT, n (%) | 18 (50.0) | 28 (51.9) | 0.863 | |
| IRRT, n (%) | 18 (50.0) | 26 (48.1) | ||
| Death at 30 days, n (%) | 0 (0) | 46 (85.2) | ||
| Death at hospital discharge, n (%) | 0 (0) | 49 (90.7) | ||
| MODS at discharge | 2 (5.6) | 54 (96.4) | P < 0.001 | |
| Cr at discharge, mmol/L | 177.83 ± 142.86 | 188.78 ± 142.46 | 0.356 | 0.722 |
| eGFR, ml/min | 59.56 ± 38.12 | 59.31 ± 45.68 | 0.026 | 0.979 |
Values are mean ± SD, median (interquartile range), or percentages.
*
The difference is statistically significant. LCOS, low cardiac output syndrome; IABP, intra-aortic balloon pump; CRRT, continuous renal replacement therapy; IRTT, intermittent renal replacement therapy; MODS, multiple organ dysfunction syndrome; Cr, creatinine; eGFR, glomerular filtration rate.