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. 2021 Oct 21;12:660230. doi: 10.3389/fimmu.2021.660230

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Copyright © 2021 Du, Zeng, Han, Zhang, Jia, Shi and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of tocilizumab and prednisone on motor function. (A) EDSS changes from the baseline to the one-year follow-up in the tocilizumab and prednisone groups. (B) Comparison of EDSS reduction rate between the wo groups. (C) HAI changes and (D) comparison between the two groups. (E) mRS changes and (F) comparison between the two groups. EDSS: expanded disability status scale; HAI: Hauser ambulation index; mRS: modified Rankin scale. * represents a significant decline in score between the current and previous follow-ups. *p < 0.05; **p < 0.01; ***p < 0.001; NS, not significant.