Table 1.
Details of the COVID-19 patients examined at presentation.
| Characteristics* | Healthy (n = 19) | Asymptomatic (n = 23) | Mild (n = 32) | Severe (n = 31) | Convalescent (n = 23) | p-value$ |
|---|---|---|---|---|---|---|
| Age in years (median)# | 27 (18-33) | 46 (6-70) | 40 (15-67) | 59 (30-85) | 26 (15-51) | |
| Male (%) | 10 (53%) | 12 (52%) | 19 (59%) | 21 (68%) | 16 (70%) | |
| Female (%) | 9 (47%) | 11 (48%) | 13 (41%) | 10 (32%) | 7 (30%) | |
| Mechanical Ventilation | NA | NA | NA | 19 (61.3%) | NA | |
| Leukocyte count (per mm3) | – | – | 6205 ± 416 | 9183 ± 961 | – | 0.007 |
| % of neutrophils | – | – | 61 ± 3 | 80 ± 2 | – | <0.0001 |
| % of lymphocytes | – | – | 29 ± 2 | 13 ± 2 | – | <0.0001 |
| Neutrophil to lymphocyte ratio | – | – | 3 ± 1 | 12 ± 3 | – | 0.007 |
| Platelets count | – | – | 237909 ± 14504 | 241300 ± 21294 | – | 0.89 |
| D-dimer (ng/mL) | – | – | 198 ± 38 | 984 ± 258 | – | 0.005 |
| CRP (mg/L) | – | – | 34 ± 13 | 206 ± 39 | – | 0.0002 |
| DEFA1 (ng/mL) | 113 ± 11 | 177 ± 44 | 230 ± 17 | 452 ± 46 | 175 ± 36 | <0.0001 |
| S100A8/A9 (Calprotectin, ng/mL) | 2288 ± 687 | 10134 ± 1236 | 16589 ± 2651 | 18183 ± 2512 | 4645 ± 899 | 0.48 |
*Values are expressed as mean ± SEM; #age in years expressed as median (range). NA denotes as not applicable. –indicates not available. $indicates statistical significance on comparison of datasets between mild and severe groups.