Table 1.
Variable | Total patients (n=76) | Steroid responder (n=46) | Steroid failure (n=30) | P-value |
---|---|---|---|---|
Age (yr) | 35.5±12.1 | 34.2±10.0 | 37.4±12.2 | 0.91 |
| ||||
Male sex | 40 (53) | 23 (50) | 17 (56) | 0.42 |
| ||||
Duration of UC prior to ASC (mo) | 12 (1–180) | 12 (1–180) | 18 (6–120) | 0.51 |
| ||||
Index presentation of UC as ASUC | 6 (8) | 4 (9) | 2 (7) | 0.53 |
| ||||
Extent | 0.92 | |||
E2 (left -sided colitis) | 20 (26) | 12 (26) | 8 (27) | |
E3 (extensive colitis) | 56 (74) | 34 (74) | 22 (73) | |
| ||||
Prior azathioprine use | 34 (45) | 21(46) | 13 (43) | 0.51 |
| ||||
Previous ASUC | 18 (24) | 9 (20) | 9 (30) | 0.73 |
| ||||
Prior systemic steroid use | 60 (79) | 35 (76) | 25 (83) | 0.61 |
| ||||
Steroid use in 1st year of diagnosis of UC | 49 (64) | 27 (59) | 22 (73) | 0.15 |
| ||||
Tobacco user | 14 (18) | 8 (17) | 6 (20) | 0.42 |
| ||||
Presence of EIMs | 27 (35) | 16 (35) | 11 (37) | 0.91 |
13 Central or peripheral arthralgia | 9 Central or peripheral arthralgia | |||
2 Episcleritis | 1 Episcleritis | |||
1 Primary sclerosing cholangitis | 1 Pyoderma gangrenosum |
Values are presented as mean±standard deviation, number (%), or median (range).
ASUC, acute severe ulcerative colitis; UC, ulcerative colitis; ASC, acute severe colitis; EIMs, extraintestinal manifestations.