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. 2020 Nov 6;19(4):438–447. doi: 10.5217/ir.2020.00055

Table 1.

Baseline Demographics and Disease Phenotypes of Patients of ASUC and Comparison of Steroid Responders with Steroid Failures

Variable Total patients (n=76) Steroid responder (n=46) Steroid failure (n=30) P-value
Age (yr) 35.5±12.1 34.2±10.0 37.4±12.2 0.91

Male sex 40 (53) 23 (50) 17 (56) 0.42

Duration of UC prior to ASC (mo) 12 (1–180) 12 (1–180) 18 (6–120) 0.51

Index presentation of UC as ASUC 6 (8) 4 (9) 2 (7) 0.53

Extent 0.92
 E2 (left -sided colitis) 20 (26) 12 (26) 8 (27)
 E3 (extensive colitis) 56 (74) 34 (74) 22 (73)

Prior azathioprine use 34 (45) 21(46) 13 (43) 0.51

Previous ASUC 18 (24) 9 (20) 9 (30) 0.73

Prior systemic steroid use 60 (79) 35 (76) 25 (83) 0.61

Steroid use in 1st year of diagnosis of UC 49 (64) 27 (59) 22 (73) 0.15

Tobacco user 14 (18) 8 (17) 6 (20) 0.42

Presence of EIMs 27 (35) 16 (35) 11 (37) 0.91
13 Central or peripheral arthralgia 9 Central or peripheral arthralgia
2 Episcleritis 1 Episcleritis
1 Primary sclerosing cholangitis 1 Pyoderma gangrenosum

Values are presented as mean±standard deviation, number (%), or median (range).

ASUC, acute severe ulcerative colitis; UC, ulcerative colitis; ASC, acute severe colitis; EIMs, extraintestinal manifestations.