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Production of SPE-A (A) and SPE-B (B) by clinical GAS isolates as determined by competitive ELISA. SPE production is depicted in arbitrary units (AU), which represent the reciprocal value of the lowest dilution of supernatant which induced ≥30% inhibition of ELISA reactivity. Invasive isolates are represented by closed dots; noninvasive isolates are represented by open dots.
