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. 2021 Oct 21;12:726448. doi: 10.3389/fendo.2021.726448

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Copyright © 2021 Xi, Jones, Mikamoto, Jiang, Faje, Nie, Labelle, Zhou, Miller, Soberman and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune checkpoint molecule mRNA expression in functioning PAs compared to non-functioning PAs. (A) Comparison of relative mRNA levels of immune checkpoint molecules between functioning PAs (gray) and non-functioning non-aggressive PAs (white). (B) Comparison of relative mRNA levels of immune checkpoint molecules between ACTH-staining PAs (gray) compared to non-functioning non-aggressive PAs (white). (C) Comparison of relative mRNA levels of immune checkpoint molecules between GH-staining PAs (gray) compared to non-functioning non-aggressive PAs (white). *p < 0.05.