Table 7.
The selected best five potential epitopes binding to MHC class II alleles, on the basis of their adjusted rank predicted by the IEDB server and epitope conservancy result.
| Number | Name | Start | End | Peptide sequence | Adjusted rank | Allele/haplotype | Epitope conservancy |
|---|---|---|---|---|---|---|---|
| (15-mer) | (conserved sequences/total) | ||||||
| 1 | TCE1(II) | 2 | 16 | LHRWLALCFLASFAV | 1.90 | HLA-DRB1*15:01 | 100% (9/9) |
| 2 | TCE2(II) | 48 | 62 | FNKYEIKGSGKKVLL | 1.60 | HLA-DRB5*01:01 | 100% (9/9) |
| 3 | TCE3(II) | 87 | 101 | TEEYNLALGERRANA | 2.40 | HLA-DRB5*01:01 | 100% (9/9) |
| 4 | TCE4(II) | 150 | 164 | VLIVECQHSVSPKKK | 3.60 | HLA-DRB5*01:01 | 100% (9/9) |
| 5 | TCE5(II) | 167 | 181 | IKWPFSFGRSAAKQD | 2.60 | HLA-DRB5*01:01 | 100% (9/9) |
The reference sequence considered in this analysis is that deduced from the genetic variant V1 (GenBank accession number MK882880). The letters found in parentheses represent the amino acids substituted in at least one of the proteins deduced from genetic variants other than the reference variant V1.