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. 2021 Oct 21;11:759894. doi: 10.3389/fonc.2021.759894
SCS single-cell sequencing
ITH intratumor heterogeneity
TME tumor microenvironment
HGP Human Genome Project
NGS next-generation sequencing
TGS third-generation sequencing
ScRNA-Seq single-cell RNA sequencing
WGS whole-genome sequencing
WTS whole-transcriptome sequencing
ATAC-Seq assay for transposase-accessible chromatin with sequencing
SnRNA-Seq single-nucleus RNA sequencing
ScChIP-Seq single-cell chromatin immunocleavage sequencing
TSCS topographic single-cell sequencing
CROP-Seq CRISPR droplet sequencing
LCM laser-capture microdissection
FACS fluorescence-activated cell sorting
IMS immunomagnetic separation
ROT Raman optical tweezers
TAS micro-total analysis system
WGA whole-genome amplification
WTA whole-transcriptome amplification
PCR polymerase chain reaction
DOP-PCR degenerative-oligonucleotide-primed PCR
MDA multiple displacement amplification
MLBAC multiple annealing- and looping-based amplification cycle
IVT in vitro transcription
GGN-ADC ground-glass nodule adenocarcinoma
TLR Toll-like receptor
VEGF vascular endothelial growth factor
SADC solid adenocarcinoma
HIF-1 hypoxia-inducible factor-1
TIMs tumor-infiltrating myeloid cells
TAMs tumor-associated macrophages
NSCLC non-small-cell lung cancer
TILs tumor-infiltrating lymphocytes
CTCs circulating tumor cells
CNV copy number variation
PDX patient-derived xenograft
HCC hepatocellular carcinoma
Tregs regulatory T cells
NASH non-alcoholic steatohepatitis
TSS transcription start site
HBV hepatitis B virus
DDX5 DEAD-box protein 5
HSCs hepatocarcinoma stem cells
EMT epithelial–mesenchymal transition
GPCR G protein-coupled receptor
FGFR fibroblast growth factor receptor
CAFs cancer-associated fibroblasts
GC gastric cancer
HDGC hereditary diffuse gastric cancer
BRD4 bromodomain-containing protein 4
IPMNs intraductal papillary myxomas
PD-L1 programmed death ligand 1
ER estrogen receptor
PR progesterone receptor
TFs transcription factors
HER2 human epidermal growth factor receptor 2
DCIS ductal carcinoma in situ
TNBC triple-negative breast cancer
NAC neoadjuvant chemotherapy
FABP4 fatty acid-binding protein 4
TRM tissue-resident memory
T-ALL T-cell acute lymphoblastic leukemia
DLBCL diffuse large B-cell lymphoma
NHL non-Hodgkin’s lymphoma
VRL vitreoretinal lymphoma
MCL mantle cell lymphoma
CTCL cutaneous T-cell lymphoma
LCH Langerhans cell histiocytosis
HCA Human Cell Atlas