FIGURE 7.

PCDH10 regulates the function of hsa_circ_0001666 on the proliferation, apoptosis and invasion of CRC cells. LoVo cells were transfected with circ NC, si‐circ, si‐circ+PCDH10 Vector, si‐circ+oe‐PCDH10, and DLD‐1 cells were transfected with circ Vector, oe‐circ, oe‐circ+PCDH10 NC, oe‐circ+si‐PCDH10. (A–C) To test the proliferative ability, CCK‐8 assays, EdU assays and colony formation assays were used (magnification, 200×; scale bar, 100 μm). (D) The Annexin‐V FITC/PI staining was used to assess the apoptotic rates. (E,F) Wound healing assays and transwell assays were performed to explore the migratory and invasive capabilities. The scale bar in wound healing assays indicated 20 μm; the scale bar in transwell assays indicated 200 μm