Table 2.
Laboratory parameters of ICU hospitalized COVID-19 patients. Low FXIII, activity level <79 %; Normal FXIII, activity level >79 %. Median and ranges are presented. Statistical significance was established by Student`s T test (NS, not significance). PT, prothrombin time; PTT, partial thromboplastin time; Neut, total neutrophils count; CRP, C-reactive protein; ALB, albumin, GGT, gamma-glutamyl transferase; ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate aminotransferase; TBIL, total bilirubin. Normal FXIII activity was defined as activity level >79 %. Low FXIII levels were levels were defined as activity level <79 %
| Parameter | Normal range | Overall (N=34) |
Low FXIII (<79 %) (N=25) |
Normal FXIII (>79 %) (N=9) |
Significance |
|---|---|---|---|---|---|
| PT (sec) | 10.03-12.43 | 11.2 (10.1-19.8) | 11.15 (10.1-19.8) | 11.3 (10.3-12.9) | NS |
| PTT (sec) | 25-34 | 28.2 (20.5-54.3) | 27.9 (21.4-54.3) | 28.7 (20.5-33.4) | NS |
| Neut X103/µl | 1.4-6 | 8.4 (3.2-27.5) | 9.2 (3.2-27.5) | 8.3 (5-13.5) | NS |
| CRP (mg/L) | 0.03-5 | 101.2 (0.3-499.4) | 102.33 (1.35-499.4) | 81.13 (0.3-293.2) | NS |
| ALB (mg/dL) | 35-50 | 29.3 (15.2-38.5) | 26 (15.2-38.5) | 32 (24-34.8) | P<0.05 |
| GGT (U/L) | 6-42 | 149.5 (18-1204) | 158 (39-1204) | 81 (18-567) | NS |
| ALP (U/L) | 46-116 | 108 (45-412) | 111 (49-412) | 75 (45-372) | NS |
| ALT (U/L) | <40 | 46.5 (45.5-967) | 45 (10-967) | 46 (14-293) | NS |
| AST (U/L) | <41 | 48.5 (16-1344) | 46 (18-1344) | 57 (16-130) | NS |
| TBIL (mg/dL) | <1.2 | 0.36 (0.1-5.24) | 0.31 (0.1-5.24) | 0.37 (0.24-0.86) | NS |