Table 2. Multivariable Analysis of Patient Characteristics Associated With Melanoma Detection on a Routine Skin Check or Found Incidentally, Compared With Patient-Detected Presentationa.
| Patient characteristic | Patient detected (referent group), No. | Found incidentally | Routine skin check | P valueb | ||
|---|---|---|---|---|---|---|
| No. | Odds ratio (95% CI)c | No. | Odds ratio (95% CI)c | |||
| Sex | ||||||
| Male | 636 | 199 | 1 [Reference] | 579 | 1 [Reference] | .003 |
| Female | 512 | 94 | 0.74 (0.55-0.98) | 279 | 0.73 (0.60-0.89) | |
| Age, y | ||||||
| <40 | 163 | 6 | 1 [Reference] | 41 | 1 [Reference] | <.001 |
| 40-49 | 177 | 17 | 2.50 (0.96-6.53) | 60 | 1.29 (0.81-2.04) | |
| 50-59 | 213 | 50 | 5.74 (2.39-13.80) | 166 | 2.89 (1.92-4.34) | |
| 60-69 | 236 | 81 | 8.20 (3.47-19.38) | 206 | 3.26 (2.18-4.88) | |
| 70-79 | 217 | 73 | 7.56 (3.18-18.00) | 230 | 3.78 (2.52-5.67) | |
| ≥80 | 142 | 66 | 10.33 (4.30-24.8) | 155 | 3.94 (2.57-6.05) | |
| Previous melanoma | ||||||
| No | 1006 | 227 | 1 [Reference] | 650 | 1 [Reference] | <.001 |
| Yes | 93 | 57 | 2.06 (1.41-3.03) | 183 | 2.36 (1.77-3.15) | |
| Unknown | 49 | 9 | 0.68 (0.31-1.47) | 25 | 0.78 (0.46-1.34) | |
| Family history of melanoma | ||||||
| No | 794 | 191 | 1 [Reference] | 572 | 1 [Reference] | .35 |
| Yes | 99 | 15 | 0.77 (0.42-1.38) | 75 | 1.13 (0.80-1.59) | |
| Unknown | 255 | 87 | 1.26 (0.91-1.73) | 211 | 1.02 (0.80-1.29) | |
| Many moles | ||||||
| No | 750 | 196 | 1 [Reference] | 537 | 1 [Reference] | .02 |
| Yes | 223 | 62 | 1.17 (0.82-1.65) | 225 | 1.39 (1.10-1.77) | |
| Unknown | 175 | 35 | 0.80 (0.53-1.22) | 96 | 0.81 (0.61-1.09) | |
| Socioeconomic statusd | ||||||
| 1st Quintile (lowest) | 123 | 34 | 1 [Reference] | 82 | 1 [Reference] | .36 |
| 2nd Quintile | 233 | 54 | 0.80 (0.48-1.32) | 147 | 0.90 (0.62-1.30) | |
| 3rd Quintile | 296 | 84 | 0.93 (0.58-1.49) | 218 | 1.00 (0.70-1.41) | |
| 4th Quintile | 199 | 50 | 0.90 (0.54-1.50) | 145 | 1.02 (0.70-1.49) | |
| 5th Quintile (highest) | 297 | 71 | 0.88 (0.53-1.44) | 266 | 1.32 (0.93-1.89) | |
| Residential remoteness | ||||||
| Major cities | 490 | 120 | 1 [Reference] | 367 | 1 [Reference] | .003 |
| Inner regional | 439 | 125 | 1.17 (0.86-1.61) | 386 | 1.34 (1.07-1.67) | |
| Outer regional | 205 | 46 | 0.88 (0.57-1.37) | 103 | 0.79 (0.57-1.09) | |
| Remote or very remote | 14 | 2 | 0.57 (0.12-2.66) | 2 | 0.23 (0.05-1.04) | |
a
This analysis was based on 2299 patients, as it excluded 153 patients with “other” recorded for how the melanoma presented.
b
P value from Wald χ2 test for overall association between predictor variable and 3-level outcome, ie, compares the odds ratios across the 3 modes of detection.
c
From multinomial logistic regression model, adjusted for all other variables in the table.
d
Index of Relative Socioeconomic Disadvantage, based on postcode of residence.