Figure 6. SFRP1 induces HIF target genes' upregulation during neuroinflammation.

1. Ingenuity Pathway Analysis network representation of NF‐κB and HIF downstream targets for CX₃CR1^{GFP /+} and CX₃CR1^{GFP /+} ;Sfrp1 ^−/− microglial cells. Coloured by Z‐score alteration of their expression after LPS stimulus.
2. Integrative Genomics Viewer transcription profile of represented genes in microglial cells isolated for saline‐ and LPS‐treated CX₃CR1^{GFP /+} and CX₃CR1^{GFP /+} ;Sfrp1 ^−/− mouse brains. Scale bar: 2 Kbp.