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. 2021 Aug 23;22(11):e52061. doi: 10.15252/embr.202052061

Figure 5. H2A.Z.1 effect on cell cycle is linked to MYC expression.

Figure 5

  1. Mitotic index (number of mitotic cells/mitotic + interphase cells) of HeLa cells after control si, H2A.Z.1 si or H2A.Z.1 si + GFP:cMYC. Error bars represent standard deviation from two biological replica (control si N = 1,033; H2A.Z.1 si N = 1,042; H2A.Z.1 si + GFP:cMYC N = 1,024). Data sets were statistically analysed using Chi‐square test. *P < 0.05; **P < 0.01; ***P < 0.001.
  2. Correlation of H2AFZ (H2A.Z.1) expression levels with MYCN status, cancer stage and risk incidence in neuroblastoma patients obtained from R2 genomics.
  3. Kaplan–Meier survival curve for neuroblastoma patients with low (red) or high (blue) expression of H2AFZ (H2A.Z.1) obtained from R2 genomics.