Table 2. Drug Release Kinetics for Different IPN Beads.
zero-order |
first-order |
Hixson–Crowell |
Higuchi |
Korsmeyer–Peppas |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
batch code | K0 (h–1) | r2 | K1 (h–1) | r2 | KHC (h–1/3) | r2 | KH (h–1/2) | r2 | KKP (h–n) | r2 | n |
F-1 | 9.8951 | 0.7529 | –0.0695 | 0.7815 | –0.5830 | 0.7360 | 27.7553 | 0.9300 | 0.0953 | 0.8643 | 1.19 |
F-2 | 11.7629 | 0.9019 | –0.0730 | 0.9326 | –0.6720 | 0.8868 | 24.6718 | 0.9263 | 0.0083 | 0.8587 | 2.53 |
F-3 | 3.1557 | 0.9239 | –0.0151 | 0.9315 | –0.4117 | 0.8403 | 30.7839 | 0.9325 | 0.0087 | 0.8903 | 1.86 |
F-4 | 12.8971 | 0.9633 | –0.0855 | 0.9811 | –0.6702 | 0.9217 | 30.6813 | 0.9353 | 0.0157 | 0.9566 | 2.22 |
F-5 | 13.3434 | 0.9456 | –0.0918 | 0.9387 | –0.6698 | 0.9171 | 31.5819 | 0.9351 | 0.0190 | 0.9064 | 2.07 |
F-6 | 8.96 | 0.8612 | –0.0581 | 0.9155 | –0.5772 | 0.7721 | 24.9156 | 0.9311 | 0.0432 | 0.8053 | 1.59 |
F-7 | 10.7271 | 0.9012 | –0.0653 | 0.8505 | –0.5987 | 0.9680 | 27.5439 | 0.9206 | 0.0129 | 0.8662 | 1.94 |
F-8 | 7.0802 | 0.9697 | –0.0384 | 0.9522 | –0.5198 | 0.9217 | 30.6269 | 0.9467 | 0.0183 | 0.9805 | 1.71 |
F-9 | 10.2180 | 0.9564 | –0.0623 | 0.9219 | –0.5857 | 0.9457 | 27.5957 | 0.9286 | 0.0212 | 0.9911 | 1.79 |