Figure 1.
The genomic organization of SARS-CoV-2 and spike protein structure. (1) The structure of SARS-CoV-2 containing an RNA as genetic material with four distinguished structural proteins like spike glycoprotein (S), membrane protein (M), envelop protein (E), and nucleocapsid (N), (2) the genomic organization of the SARS-CoV-2 with 16 Nsps along with the structural and the accessory proteins gene (from 5ʹ end to 3ʹ end), and (3) spike glycoprotein structure with two subunits S1 and S2 that are targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion) where S1 contains a receptor binding domain (RBD); S1 has a C-terminal domain (CTD) and an N-terminal domain (NTD)