Table 2.

Presence of cognitive impairment and frailty in relation to other geriatric impairments and demographic and clinical characteristics among older patients with atrial fibrillation, SAGE-AF 2016-2018, OR (95% confidence interval)^*

	Frailty only	CI only	Frailty and CI
	N=419 (33.7)	N=64 (5.1)	N=108 (8.7)
Other geriatric impairment
Vision impairment	1.42 (0.79, 2.58)	1.07 (0.79, 1.45)	1.17 (0.71, 1.93)
Hearing impairment	0.44 (0.23, 0.84)	1.32 (0.99, 1.76)	0.96 (0.58, 1.60)
Social isolation	1.30 (0.56, 3.04)	1.66 (1.10, 2.50)	1.01 (0.47, 2.17)
Elevated symptoms of depression	10.16(5.17, 19.96)	1.11 (0.76, 1.62)	4.62 (2.59, 8.26)
Elevated symptoms of anxiety	0.69 (0.35, 1.34)	1.19 (0.81, 1.75)	1.68 (0.94, 3.00)
Any fall in the past 6 months	2.11 (1.15, 3.87)	0.99 (0.71, 1.40)	1.14 (0.66, 1.98)
Demographic characteristics
Age (5 year increments)	1.20 (0.97, 1.50)	1.48 (1.32, 1.66)	1.56 (1.29, 1.88)
Less than college graduate	1.33 (0.73, 2.43)	2.03 (1.52, 2.70)	3.81 (2.13, 6.81)
Non-Hispanic white	0.75 (0.26, 2.15)	5.26 (3.43, 8.07)	7.94 (4.34, 14.55)
Not married	1.30 (0.72, 2.34)	0.93 (0.70, 1.25)	0.96 (0.58, 1.58)
Clinical characteristics
CHA2DS2VASC	1.32 (1.06, 1.64)	1.07 (0.96, 1.19)	1.35 (1.13, 1.62)
HAS-BLED	0.99 (0.75, 1.32)	1.19 (1.04, 1.37)	1.43 (1.12, 1.81)
AMI	2.79 (1.46, 5.35)	0.90 (0.61, 1.31)	0.88 (0.48, 1.62)
Asthma/COPD	1.51 (0.83, 2.77)	0.99 (0.72, 1.37)	1.33 (0.80, 2.24)

^*Referent group is those who are not impaired (n=653).