Table 2.
Presence of cognitive impairment and frailty in relation to other geriatric impairments and demographic and clinical characteristics among older patients with atrial fibrillation, SAGE-AF 2016-2018, OR (95% confidence interval)*
| Frailty only | CI only | Frailty and CI | |
|---|---|---|---|
| N=419 (33.7) | N=64 (5.1) | N=108 (8.7) | |
| Other geriatric impairment | |||
| Vision impairment | 1.42 (0.79, 2.58) | 1.07 (0.79, 1.45) | 1.17 (0.71, 1.93) |
| Hearing impairment | 0.44 (0.23, 0.84) | 1.32 (0.99, 1.76) | 0.96 (0.58, 1.60) |
| Social isolation | 1.30 (0.56, 3.04) | 1.66 (1.10, 2.50) | 1.01 (0.47, 2.17) |
| Elevated symptoms of depression | 10.16(5.17, 19.96) | 1.11 (0.76, 1.62) | 4.62 (2.59, 8.26) |
| Elevated symptoms of anxiety | 0.69 (0.35, 1.34) | 1.19 (0.81, 1.75) | 1.68 (0.94, 3.00) |
| Any fall in the past 6 months | 2.11 (1.15, 3.87) | 0.99 (0.71, 1.40) | 1.14 (0.66, 1.98) |
| Demographic characteristics | |||
| Age (5 year increments) | 1.20 (0.97, 1.50) | 1.48 (1.32, 1.66) | 1.56 (1.29, 1.88) |
| Less than college graduate | 1.33 (0.73, 2.43) | 2.03 (1.52, 2.70) | 3.81 (2.13, 6.81) |
| Non-Hispanic white | 0.75 (0.26, 2.15) | 5.26 (3.43, 8.07) | 7.94 (4.34, 14.55) |
| Not married | 1.30 (0.72, 2.34) | 0.93 (0.70, 1.25) | 0.96 (0.58, 1.58) |
| Clinical characteristics | |||
| CHA2DS2VASC | 1.32 (1.06, 1.64) | 1.07 (0.96, 1.19) | 1.35 (1.13, 1.62) |
| HAS-BLED | 0.99 (0.75, 1.32) | 1.19 (1.04, 1.37) | 1.43 (1.12, 1.81) |
| AMI | 2.79 (1.46, 5.35) | 0.90 (0.61, 1.31) | 0.88 (0.48, 1.62) |
| Asthma/COPD | 1.51 (0.83, 2.77) | 0.99 (0.72, 1.37) | 1.33 (0.80, 2.24) |
*
Referent group is those who are not impaired (n=653).