Table 1.
Detailed information of the 20 DEG with the lowest FDR.
| Gene symbol | GO annotation | FDR | log2FC |
|---|---|---|---|
| AKR1B10 | NADP+1-oxidoreductase activity, fatty acid metabolic process, positive regulation of cell death, lipid catabolic process, oxidation-reduction process, regulation of lipid biosynthetic process | 3.43E-31 | −3.33444 |
| C1orf198 | Response to stimulus | 2.63E-19 | −2.39293 |
| DDH3 | NADP+1-oxidoreductase activity, positive regulation of cell proliferation, oxidoreductase activity, cellular response to reactive oxygen species, positive regulation of reactive oxygen species metabolic process | 1.02E-08 | −1.89136 |
| ACSM3 | Fatty acid biosynthetic process, phospholipid biosynthetic process, fatty acid ligase activity | 7.37E-08 | −1.02436 |
| FERMT1 | Cell adhesion, regulation of cell–cell adhesion mediated by integrin, establishment of epithelial cell polarity | 9.98E-06 | −1.01197 |
| A2M | Negative regulation of complement activation, lectin pathway, negative regulation of endopeptidase activity, stem cell differentiation | 1.90E-05 | −1.55168 |
| SGK1 | Apoptotic process, defense response, cellular response to DNA damage stimulus, regulation of cell adhesion, lipopolysaccharide-mediated signaling pathway, regulation of cellular protein metabolic process, regulation of cell cycle | 5.81E-05 | −1.19952 |
| ICAM3 | Immune system process, integrin binding, single organismal cell–cell adhesion | 6.48E-05 | −1.0813 |
| LYPD1 | Unknown | 0.000104 | −1.31005 |
| PLLP | Ion transport, integral component of membrane | 0.000212 | 1.428531 |
| C21orf5 | Macromolecule metabolic process, cellular response to stimulus | 0.000235 | 1.287287 |
| CHI3L2 | Carbohydrate metabolic process, inflammatory response, positive regulation of angiogenesis | 0.000276 | −1.40479 |
| NEDD9 | Animal organ morphogenesis, regulation of cellular process, cellular response to stimulus | 0.000349 | −1.34656 |
| CLRN2 | Integral component of membrane | 0.000432 | 1.16737 |
| ZBTB16 | Negative regulation of cell proliferation, positive regulation of apoptotic process | 0.000793 | −1.15451 |
| KRTAP5-AS1 | Regulation of metabolic process | 0.00088 | −1.28645 |
| CCDC80 | Fibronectin binding, protein binding, positive regulation of cell-substrate adhesion, cellular metabolic process | 0.00295 | −1.2423 |
| LOC514257 | Transporter activity, transmembrane transport | 0.00295 | −1.09758 |
| PLEKHF1 | Apoptotic process, positive regulation of autophagy, cellular response to stimulus | 0.00295 | 1.144043 |
| HAMP | Hormone activity, cellular iron ion homeostasis, defense response to bacterium | 0.003941 | −1.14331 |
DEG = differentially expressed genes; FDR = false discovery rate; GO = Gene Ontology; FC = fold change.